… Our aim was to test associations between genetic polymorphisms involved in the absorption
and metabolism of CsA and TAC, and drug disposition variables in two groups of Chilean …

… data obtained from Spanish Caucasians, particularly from the northern region of Spain and
to the … Influence of genotype and haplotype of MDR1 (C3435T, G2677A/T, C1236T) on the …

… The human MDR1 gene mutation at exon 26, position 3435 (also known as C3435T) leads
… Although the C3435T mutation in exon 26 of the MDR1 gene is a silent mutation, this poly‑ …

… The present meta-analysis is performed to determine the association of C1236T and
C3435T polymorphisms in the MDR1 gene. Google Scholar, PubMed, and Science Direct were …

… the contribution of the C3435T polymorphism to disease risk in … the single nucleotide
polymorphism (SNP) C3435T by using the … (Spain) found a significant association between the …

… Genotype C1236T and C3435T of MDR-1 gene had no significant effect on Tac dose
requirement. Patients having CYP3A5*1/*1(expresser) and TT/AA (homozygous mutant) of …

… Of these three SNPs, C1236T and C3435T are silent polymorphisms. While C1236T does
not affect protein expression or mRNA stability, altered mRNA, and protein expression levels …

… ABCB1 common polymorphisms (ie, C3435T, or … Spanish legislation on clinical research
in humans and was approved by the Research Ethics Committee, authorized by the Spanish …

… of Helsinki and with the Spain's current legislation on clinical … suggest that patients carrying
the C3435T, C1236T, or G2677T/… Some studies relate ABCB1 C3435T polymorphism to a …

… Our results indicated that C3435T polymorphisms did not affect PFS and OS, whereas …
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-…